amixon® mixer-dryer reactors combine chemical synthesis, gentle mixing, vacuum drying, and full discharge into one seamless, closed process. Designed to meet the strict demands of modern pharmaceutical manufacturing, these systems offer unmatched control, hygiene, and process efficiency.

Request a Pilot Test

Experience how amixon® technology optimizes your API workflow—from wet to dry—in a validated, hygienic, and space-saving solution.

Integrated Performance for Regulated Pharmaceutical Environments

Today’s pharmaceutical manufacturing demands precision, process integrity, and full regulatory alignment. amixon® mixer-dryer reactors meet those expectations—combining synthesis, gentle mixing, vacuum drying, and hygienic discharge in a single, fully contained vessel.

From biologics and small-molecule APIs to intermediates and crystalline actives, these systems are engineered to deliver consistent results across every batch, while streamlining workflows and reducing complexity in validation.

Gentle Mixing That Preserves Product Quality

Low-shear, spiral-blade agitators gently process slurries, viscous suspensions, or fragile crystal structures—preventing particle breakage and degradation. This ensures higher yields and more stable product properties, especially important in high-potency and temperature-sensitive applications.

Uniform Heating with Vacuum Drying Built In

With jacketed walls and internal heat transfer surfaces, thermal control is precise and uniform—supporting exothermic reactions, crystallization, or solvent evaporation. The integrated vacuum drying function enables fast, low-temperature drying, reducing energy usage and residual solvent levels in line with ICH Q3C guidelines.

Gas-Tight Discharge. Zero Cross-Contamination.

amixon® reactors are engineered for full product discharge in a closed system, protecting product integrity and worker safety. Especially in multi-product environments, this eliminates cross-contamination risks and reduces cleaning effort—ideal for GMP-compliant production facilities.

Why Leading API Manufacturers Trust amixon®

  • Hygienic design engineered to meet industry regulations
  • Gentle processing for sensitive, high-value actives
  • High recovery rates and minimal cleaning effort
  • Scalable from bench testing to commercial output

Original blog entry here.